Tacrolimus Suppositories in Therapy-Resistant Ulcerative Proctitis
نویسندگان
چکیده
منابع مشابه
Ulcerative Proctitis
Ulcerative colitis (UC) is a chronic inflammatory disease of digestive tract of unknown cause. This disease is characterized by a chronic course with alternating periods of activity and clinical remission. The incidence of UC in America has a range extending from 2.2 to 14.3 per 100,000 population per year [1]. The continuous involvement from the rectum to proximal presents an extension that is...
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Nonsteroidal anti inflammatory drugs are widely prescribed because of their high efficacy as both anti-inflammatory and analgesic agents. The adverse effects ofNSAIDs such as damage to the gastroduodenal mucosa, renal toxicity and bronchospasm are well known. In recent years, many cases have been reported ofNSAID induced damage to the small and large intestine.",2 We report a case ofacute ischa...
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BACKGROUND Efficacy of infliximab in treating ulcerative proctitis remains unknown. AIM To evaluate the clinical, biological and endoscopic efficacy of infliximab therapy in refractory proctitis. METHODS The charts of 420 patients treated with infliximab for ulcerative colitis were reviewed. Thirteen patients were treated with infliximab for refractory ulcerative proctitis in six referral c...
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Ulcerative colitis (UC)-associated pan-enteritis is a newly identified clinical entity that occurs almost exclusively after colectomy. Characterized by diffuse small bowel mucosal inflammation not compatible with Crohn's disease, the optimal treatment modality for this condition is unknown. Tacrolimus is a potent calcineurin inhibitor that has been successfully used in the treatment of UC. We d...
متن کاملRefractory Ulcerative Proctitis—A Brief Review
Ulcerative proctitis (UP) is a common condition in adult patients and can be very difficult to treat. This review considers critically the definition of this entity, its epidemiology and course, and the modes of therapy currently available. Therapies currently in development are considered as well.
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ژورنال
عنوان ژورنال: Inflammatory Intestinal Diseases
سال: 2018
ISSN: 2296-9403,2296-9365
DOI: 10.1159/000493979